Comparing the effects of Ketamine-Fentanyl and Propofol-Fentanyl on Anesthesia Process

Comparative Evaluation of Ketamine-Fentanyl and Propofol-Fentanyl on Hemodynamic Changes of Laryngeal Mask Airway Insertion and Post Anesthesia Complications in Inguinal Herniorrhaphy Surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014070618375N1

Enrollment

120

Registered

2014-09-14

Start date

2014-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes during insertion of Laryngeal Mask Airway and post anesthesia complications after using Ketamine-Fentanyl and Propofol-Fentanyl.

Interventions

Intervention 1: Intervention Group: Fentanyl 3 µ/kg and after 3 minutes Ketamine 2 mg/kg, Atrachorium 0.3 mg/kg is intravenously injected and after 3 minutes appropriate Laryngeal Mask Airway is inser

Treatment - Drugs

Intervention Group: Fentanyl 3 µ/kg and after 3 minutes Ketamine 2 mg/kg, Atrachorium 0.3 mg/kg is intravenously injected and after 3 minutes appropriate Laryngeal Mask Airway is inserted.

Control Group: Fentanyl 3 µ/kg and after 3 minutes Propofol 2 mg/kg, Atrachorium 0.3 mg/kg is injected and after 3 minutes appropriate Laryngeal Mask Airway is inserted.

Eligibility

Sex/Gender

All

Age

16 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Patients who are candidate for Herniorrhaphy surgery Exclusion Criteria: Hemodynamic instability; History of psychotic disorder; Brain injury or intracranial lesion; ASA class 3 or more; History of reaction to anesthetic drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Vomiting. Timepoint: During the recovery. Method of measurement: Observation.;Agitation. Timepoint: During the recovery. Method of measurement: Richmond Agitation Sedation Scale (RASS).;Heart Rate. Timepoint: 1, 3, 5, 10 min. Method of measurement: Beat per minute.;Blood Pressure. Timepoint: 1, 3, 5, 10 min. Method of measurement: mm Hg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hajijafari

Kashan University of Medical Sciences

dr_hajijafari@kaums.ac.ir+98 31 5533 9292

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026