epidermal melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group will be received parsley tail((20 g parsley for 5 minutes in a liter of boiling water, brewed, smooth and leave to cool) to 8 weeks topically once at night. Interv
Treatment - Other
Treatment - Drugs
Intervention group will be received parsley tail((20 g parsley for 5 minutes in a liter of boiling water, brewed, smooth and leave to cool) to 8 weeks topically once at night.
Control group will be received hydroquinone cream to 8 weeks to receive Thin layer and topically once at night.
Sponsors
Vice chancellor for research of Gonabad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women 50-15 years old (childbearing age); willingness to cooperate in the project; having of epidermal melasma, non-pregnant; Not lactating, not using anti-smudge drugs in the past 30 days , non-contraceptive therapy during the study;No history of epilepsy, liver, thyroid and asthma diseases, no history of allergy to hydroquinone, the lack of any kind of sensitivity to the families Apiaceae plants such as carrots, celery and parsley; not employed in occupations requiring long-term exposure to sunlight (farmers and laborers); Exclusion criteria: pregnancy occurs; sensitivity to hydrocarbons and parsley ; diseases affecting the severity of skin disease and treatment interaction, unwillingness to continue treatment.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epidermal melasma. Timepoint: before and after intervention. Method of measurement: The melasma severity index and wood lamp. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahide Ramezani
Gonabad University of Medical Sciences
Outcome results
None listed