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The antioxidant effects of Q10 co enzyme on oxidative stress and lipid per oxidation among gastric patients infected by h.pylori

Anti oxidant properties of Q10 co enzyme and their effects on oxidative stress and lipid per oxidation among patients infected by h. pylori

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014070118310N1
Enrollment
100
Registered
2014-09-10
Start date
2014-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastritis. Chronic gastritis, unspecified

Interventions

Intervention 1: Intervention group: Using three drugs regimen (bismuth sub citrate (120mg/kg QD), tetracycline (500mg QD) and metronidazole (400 mg/kg TD)) + Q10 coenzyme (2 mg/kg/day) for 6 weeks. Th
Treatment - Drugs
Intervention group: Using three drugs regimen (bismuth sub citrate (120mg/kg QD), tetracycline (500mg QD) and metronidazole (400 mg/kg TD)) + Q10 coenzyme (2 mg/kg/day) for 6 weeks. The types and dos
Control group: Using three drugs regimen (bismuth sub citrate (120mg/kg QD), tetracycline (500mg QD) and metronidazole (400 mg/kg TD)) + placebo (lactolose) for 6 weeks. The types and dosages of drug

Sponsors

Vice Chancellor for researchesand Technology, Ilam University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Including criteria: h. pylori infected gastric patients Excluding criteria: pregnancy; lactation; recent antibiotic application (6 recent weeks); recent attempt for h. pylori treatment; recent surgery of stomach; positive history of alcohol consumption or addiction; having infections or malignancies in other organs; cardiovascular diseases; diabetes; IBD .

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Total antioxidant capacity (TAC). Timepoint: Start and end of study. Method of measurement: Serum level of studied marker by standard kits.;Glutation peroxidise. Timepoint: Start and end of study. Method of measurement: Serum level of studied marker by standard kits.;Malondialdehyde. Timepoint: Start and end of study. Method of measurement: Serum level of studied marker by standard kits.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Asadollahi Ruhangiz

Ilam University of Medical Sciences

roohiasadollahi@yahoo.com+98 22 27126

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026