Postoperative Catheter-related Bladder Discomfort in Patients Undergoing open prostatectomy. Mechanical complication of urinary (indwelling) catheter
Conditions
Interventions
Intervention 1: patients in gabapentin group will received the study drug orally with sips of water 2 hours before the administration of spinal anesthesia then they will receive gabapentin capsules 1
Treatment - Drugs
patients in gabapentin group will received the study drug orally with sips of water 2 hours before the administration of spinal anesthesia then they will receive gabapentin capsules 100 mg per 8 hour
matching placebo capsules contain starch will be given to placebo group
Sponsors
Arak University of Medical Science,Office of Vice Chancellor for Research
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: inclusion criteria: Patients of American Society of Anesthesiologists (ASA) physical status I-II undergoing elective open prostatectomy surgery under spinal anesthesia ; requiring catheterization of the urinary bladder ; 50–80 kg of weight exclusion criteria: Patients with history of OAB (urinary frequency >3 times at night and > 8 times in 24 hours) ; neurogenic bladder; diabetes mellitus ; Parkinson’s disease and impaired renal function ; chronic use of opiates or sedatives ; antiacid uptake in the past 48 hours ; hypersensitivity to amide local anesthetics or gabapentin
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Catheter-related bladder discomfort(CRBD) severity. Timepoint: at hours 2,5,24,48,72 after surgery. Method of measurement: based on asking patients based on Likert scale.;Pain severity. Timepoint: at hours 2,5,24,48,72 after surgery. Method of measurement: based on VAS index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total morphine requirement. Timepoint: at hours 2,6,24,48,72. Method of measurement: counting amount of morphine that will be injected to patient.;Postoperative sedation. Timepoint: at hours 2,6,24,48,72. Method of measurement: clinical examination.;Postoperative N/V. Timepoint: at hours 2,6,24,48,72. Method of measurement: clinical examination and history taking. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJavad Aghamohammadi
Medicine faculty , Aarak University of Medical Science
Outcome results
None listed