Comparison of Nd-Yag fractional 1064 laser therapy with tranexamic acid mesotherapy efficacy versus Nd-Yag fractional 1064 laser therapy with oral tranexamic acid in patients suffering melasma.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140624018210N9

Enrollment

Registered

2019-04-13

Start date

2018-06-22

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

melasma.

Interventions

Intervention group:.

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: patients should have the classical clinical features of melasma. skin type of patients should be I to IV. patients age should be between 18 to 50.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Brightening and improving the appearance of melasma by MASI score. Timepoint: Before the begin of the intervention and then 2, 4, 6, 8, 10, 12 weeks after the treatment in the studied groups. Method of measurement: The device used is Visioface, a scale used in study is melasma area severity index, and a questionnaire on the patient's healing process has also been used.	—

Secondary

Measure	Time frame
Side effect of treatment , tolerability , satisfaction. Timepoint: 2, 4, 6, 8, 10, 12, 16 weeks after each treatment stage. Method of measurement: by questionnairr.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham behrangi

Iran University of Medical Sciences

Mahsa.shemshadi@gmail.com+98 21 6435 2391

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026