Healthy persons exposed to petrochemical pollutants.. Occupational exposure to toxic agents in other industries
Conditions
Interventions
Intervention 1: One capsule of placebo and 100 grams of ordinary yogurt. Intervention 2: Probiotics capsule twice a day and 100 grams of ordinary yogurt. Intervention 3: 100 grams of probiotics yogurt
Placebo
Treatment - Drugs
One capsule of placebo and 100 grams of ordinary yogurt.
Probiotics capsule twice a day and 100 grams of ordinary yogurt
100 grams of probiotics yogurt and placebo
Sponsors
Petrochemical Research & Technology Co.+ Vice Chancellor of Research, Iran University of Medical Sc
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Having the willingness to participate in the study and signing an informed consent form; 2. Having at least one-year work experience in Petrochemical Research & Technology Co.; 3. Aging between 20 and 60; 4. Having good physical health conditions based on the clinical history; 5. Not using nutritional supplements in the last 2 months; 6. Not taking medicines (anti-depression, NSAID, etc.); 7. GHQ score of equal or more than 9. Exclusion Criteria: 1. Smoking cigarettes in the last year; 2. Having an unwillingness to participate; 3. Not following the treatment (using less than 80% of yogurts or supplements); 4. Having physical sickness or taking any kind of medicine or supplements during the intervention.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fat intake. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: The 24-Hour Dietary Recall Questionnaire.;Mental health. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: GHQ (General Health Questionnaire).;Neuropeptide Y (NPY). Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;CORTISOL. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;( Adrenocorticotropic hormone)ACTH. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Carboniylated Protein. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Kynurenine (KYN). Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Isoprostane F2a. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Hydroxydeoxyguanosine (8-OHdG). Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Oxidized low-density lipoprotein (Ox-LDL). Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Interferon gamma (IFN?). Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Tryptophan. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Blood Test.;Physical Activity. Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: International Physical Activity Questionnaire(IPAQ).;Age. Timepoint: Beginning of the study. Method of measurement: Question.;Height. Timepoint: Beginning of the study. Method of measurement: Height measurement with Seca Stadiometer.;Body mass index (BMI). Timepoint: At the begininng of the study and the end of 6th week. Method of measurement: Weight in Kilog | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Akbar Mohammadi
Iran University of Medical Sciences
Outcome results
None listed