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Effect of ECT on treatment of medically refractory epilepsy

Adjunctive treatment use of electroconvulsive therapy in seven patients with Lennox-Gastaut syndrome and medically-refractory epilepsy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014062111778N2
Enrollment
7
Registered
2014-10-25
Start date
2014-04-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy. Lennox-Gastaut syndrome

Interventions

1-each patient compare with himself 2-bitemporal ECT as below:3 times aweak for the first month and weakly for the 3 months after 3-adjusting minimal energy for ECT device that induces clinical seizur
Treatment - Other
1-each patient compare with himself 2-bitemporal ECT as below:3 times aweak for the first month and weakly for the 3 months after 3-adjusting minimal energy for ECT device that induces clinical seiz

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were: male / female patients, age five years and older? diagnosis of LGS made on the basis of electro-clinical findings? medically-refractory seizures defined as failure of two or more AEDs at maximal tolerated doses and one or more disabling seizures (e.g., generalized tonic-clonic seizures and / or drop attacks) per week? They had stable medication regimen for four weeks prior to entry? Informed consent by patients was obtained? Exclusion criteria were: Patients younger than 5 y/o; patients with progressive neurological conditions; having any serious medical (particularly cardiac) illness or major psychiatric disorder or history of psychogenic non-epileptic seizures.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Decreasing seizure frequensy. Timepoint: comparing seizure frequensy 10-16 and 22 weaks after intervention to 4 weaks befor. Method of measurement: seizure frequensy calendar.

Secondary

MeasureTime frame
Intervention compliance. Timepoint: weakly. Method of measurement: frequent visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Mohammad Ali Razavizadegan Jahromi

NAJA

mrazavizadegan@yahoo.com+98 71 1218 8818

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026