post operative pain control

Preoperative single dose of oral Amantadine for acute and chronic post operative pain control in Mandibular fracture

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201406201772N13

Enrollment

Registered

2014-06-27

Start date

2014-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post operative pain control. Antiparkinsonism drugs

Interventions

Intervention 1: Control group: instead of Amantadine capsule, recived placebo before the operation. Intervention 2: Intervention group received Amantadine capsule 100 mg, 1-2 hours before surgery.

Treatment - Drugs

Control group: instead of Amantadine capsule, recived placebo before the operation

Intervention group received Amantadine capsule 100 mg, 1-2 hours before surgery

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion: age from 20 to 60 people who are going to have open reduction for mandibular fracture Exclusion criteria : Addiction, Seizure, psychopathic conditions and refuse to participate.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 0, 2, 4, 6, 12 and 24 hours after operation. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Opioid cosumption. Timepoint: 0, 2, 4, 6, 12 and 24 hours after operation. Method of measurement: Total Dose.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDawood Aghamohammadi

Tabriz university of medical science/fuculty of medicin/ Anesthesiology Dept

aghamohammadid@tbzmed.ac.ir+98 41 1381 8940

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026