severe chronic urticaria. Idiopathic urticaria
Conditions
Interventions
Intervention 1: The injection of 2.5 ml of autologous serum for 9 weeks and then monthly for 3 to 6 months. Intervention 2: The injection of 2.5 ml of normal saline for 9 weeks and then monthly for 3
Treatment - Drugs
Placebo
The injection of 2.5 ml of autologous serum for 9 weeks and then monthly for 3 to 6 months.
The injection of 2.5 ml of normal saline for 9 weeks and then monthly for 3 to 6 months
Sponsors
University of Medical Sciences Shiraz
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients entered the study had severe urticaria for at least 6 weeks in most of the days; not responding to antihistamines? patients who had no other systemic disease; those with negative food allergy skin test; patients without urticaria vasculitis. Exclusion criteria: patients with systemic disease; those who had positive allergy skin test with food; those who had a good response to antihistamines.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Questionnaire. Timepoint: Before onset of treatment and end of weekly treatment and end of monthly treatment. Method of measurement: physical examination and history. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhad Abolnezhadian
Shiraz University of Medical Sciences
Outcome results
None listed