type 2 diabetes. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: Sesamine supplement, 200 mg caps per day for 8 weeks. Intervention 2: Placebo group: placebo caps for 6 weeks.
Treatment - Drugs
Intervention group: Sesamine supplement, 200 mg caps per day for 8 weeks
Sponsors
Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Main inclusion criteria: : having type 2 diabetes; 30 to 60 years old; BMI<30; Not having severe cardiovascular, hepatic, kidney, gastrointestinal, thyroid or inflammatory diseases; Not using insulin or taking corticosteroids, NSAIDS, immunosuppressives, multivitamin-mineral, fiber and omega 3 supplements since 3 weeks prior to the study and during intervention period; No smoking or addiction; No pregnancy or lactation; Not having any weight loose or weight gain regimes; No use of antibiotics. Main exclusion criteria: drug type and dose fluctuation during intervention period; unwilling to continue the study; looking sensitivity or allergy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting Blood Sugar. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;Hemoglobin A1c. Timepoint: Before and after 8 weeks. Method of measurement: Chromatography.;Total Cholesterol. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;Triglyceride. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;HDL.c. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;LDL.c. Timepoint: Befor and after 8 weeks. Method of measurement: spectrophotometry.;Hs-CRP. Timepoint: Befor and after 8 weeks. Method of measurement: ELISA.;TNF-a. Timepoint: Befor and after 8 weeks. Method of measurement: ELISA.;IL-6. Timepoint: Befor and after 8 weeks. Method of measurement: ELISA.;Adiponectin. Timepoint: Befor and after 8 weeks. Method of measurement: ELISA.;Malondialdehyde. Timepoint: Befor and after 8 weeks. Method of measurement: TBARS.;Dietary Factors. Timepoint: Befor and after 8 weeks. Method of measurement: 24h recall.;Insulin. Timepoint: Befor and after 8 weeks. Method of measurement: ELISA.;Blood Pressure. Timepoint: before and after intervention. Method of measurement: Medical mercury sphygmomanometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body weight. Timepoint: Before and after 8 weeks. Method of measurement: scale.;Waist circumference. Timepoint: Before and after 8 weeks. Method of measurement: meter.;Hip circumference. Timepoint: Before and after 8 weeks. Method of measurement: meter.;Body adiposity index. Timepoint: Before and after 8 weeks. Method of measurement: Hip circumference (cm)/height (m)1.5 – 18.;Body fat%. Timepoint: Before and after 8 weeks. Method of measurement: omron. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrnoush Zakerzadeh
School of Paramedicine, Ahvaz Jondishapur University Of Medical Sciences
Outcome results
None listed