Methicillin Resistant Staphylococcus aureus species in Septoplasty or Rhinoplasty

Can Prophylactic Postoperative Oral Antibiotic Cause Methicillin Resistant Staphylococcus aureus species (MRSA) in Septoplasty or Rhinoplasty?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140618018143N4

Enrollment

102

Registered

2018-12-09

Start date

2013-06-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septoplasty or Rhinoplasty. Acute nasopharyngitis [common cold]

Interventions

Intervention 1: Intervention group: This group received a preoperative injection of cephalothin (1 g) and postoperative oral cephalexin (500 mg 4 times a day for 7 days). Intervention 2: Control group

Eligibility

Sex/Gender

All

Age

No minimum to 60 Years

Inclusion criteria

Inclusion criteria: Patients known to be at risk for Methicillin Resistant Staphylococcus aureus species colonization and infection after surgery

Exclusion criteria

Exclusion criteria: Age older than 60 years old HIV Those with recent hospital admission Those with recent antibiotic use Immunodeficiency Upper respiratory infection

Design outcomes

Primary

Measure	Time frame
Detection of methicillin resistant staphylococcus aureus species. Timepoint: Preoperative and on 7th day postoperative. Method of measurement: The samples were cultured onto a mannitol salt agar medium for isolation of S. aureus and then incubated at 35°C overnight. The isolated bacteria were identified based on morphologic and biochemical tests. Isolated staphylococcus aureus were screened for methicillin-resistance.	—

Measure

Time frame

Detection of methicillin resistant staphylococcus aureus species. Timepoint: Preoperative and on 7th day postoperative. Method of measurement: The samples were cultured onto a mannitol salt agar medium for isolation of S. aureus and then incubated at 35°C overnight. The isolated bacteria were identified based on morphologic and biochemical tests. Isolated staphylococcus aureus were screened for methicillin-resistance.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNader Akbari Dilmaghani

Shahid Beheshti University of Medical Sciences

nadakbari@sbmu.ac.ir+98 21 23871

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026