Major depressive disorder. Depressive episode
Conditions
Interventions
Intervention 1: Melissa officinalis(each cap 500 mg)Usage: 2 cap every 12 hours for 8 weeks. Intervention 2: Fluoxetin : (each cap 5 mg)
Usage: 2 cap every 12 hours for 8 weeks. Intervention 3: Lavand
Treatment - Other
Treatment - Drugs
Melissa officinalis(each cap 500 mg)Usage: 2 cap every 12 hours for 8 weeks
Fluoxetin : (each cap 5 mg)
Usage: 2 cap every 12 hours for 8 weeks
Lavandula Angustifolia (each cap 500 mg)Usage: 2 cap every 12 hours for 8 weeks
Sponsors
Shahed University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 18 - 65 years old; DSM-V criteria for major depressive disorder(mild to moderate); signed informed consent. Exclusion criteria: positive history of other psychological disorders; consumption of alcohol or other addictive substances in last 2 weeks; serious medical disease; allergic reaction to medical herbs; positive history of suicidal attempt or suicidal intention; pregnancy; consumption of thyroid disorders drugs.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: Baseline,2 , 4 and 8 weeks after starting the medication. Method of measurement: Hamilton rating scale for depression. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side Effects. Timepoint: 0-2-4-8 weeks. Method of measurement: Clinical interview and physical examination and checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mostafa Araj Khodaei
Shahed University
Outcome results
None listed