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Acid-Base and Electrolytes Imbalance in Normal Saline and 1/6 Molar Sodium Bicarbonate Infusions during Surgical Laminectomy

Comparison of Acid-Base and Electrolytes Imbalance in Normal Saline and Bicarbonate 1/6 Molar Intravenous Fluid Infusions during Cervical and Lumbar Laminectomy: A Pilot Double-Blinded Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014061717413N4
Enrollment
40
Registered
2015-03-28
Start date
2014-07-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Nerve root and plexus compressions in intervertebral disc disorders. Condition 2: electrolyte and acid-base imbalance. Nerve root and plexus compressions in intervertebral disc disorders Other disorders of fluid, electrolyte and acid-base balance

Interventions

Intervention 1: Maintenance fluid therapy was done using normal saline and deficit fluid therapy was done using 1/6 molar sodium bicarbonate in the first group. Intervention 2: All maintenance and def
Treatment - Drugs
Maintenance fluid therapy was done using normal saline and deficit fluid therapy was done using 1/6 molar sodium bicarbonate in the first group.
All maintenance and deficit fluid therapies were done using normal saline in the second group.

Sponsors

Baqiyatallah University of Medical Sciences, Deputy of Research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 35 to 70 years old patients; with ASA class I and II; candidate for cervical and lumbar spinal laminectomy. Exclusion criteria: Patients with chronic kidney disease; hepatic failure; electrolytes imbalance; changes in blood pressure more than 30% of basal amount; needing blood transfusion before and during operation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Electrolytes imbalance. Timepoint: After the surgery. Method of measurement: Electrolytes level checking in patients' blood sample.;Acid-base imbalance. Timepoint: After the surgery. Method of measurement: Arterial blood gasses levels in patients' arterial blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Karimi-Sari

Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Tehran, IR Iran

dr.karimih@yahoo.com+98 21 8126 4354

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026