The effect of Lavandula angustifolia and Melissa officinalis on depression

Evaluation of the effect of Lavandula angustifolia and Melissa officinalis products using nasal spray method on mild to moderate depression

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140617018126N7

Enrollment

Registered

2022-11-02

Start date

2023-01-21

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Major depressive disorder, single episode, moderate

Interventions

Intervention 1: Intervention group: This group will receive Melissa Officinalis nasal spray containing one percent (one gram per hundred cc) of Melissa Officinalis. The sprays will be provided by Sina

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Having mild to moderate depression Age 18-60 years

Exclusion criteria

Exclusion criteria: History or other psychiatric illness History of allergy to herbal medicines Taking psychiatric or herbal medicines during the last 2 weeks Having severe or chronic medical diseases Pregnant and lactating women History of suicide attempts Having hypothyroidism and high blood pressure

Design outcomes

Primary

Measure	Time frame
The level of depression. Timepoint: Week 0, 3 and 6. Method of measurement: Visit by psychiatrist and Hamilton questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mostafa Araj khodaie

Tabriz University of Medical Sciences

araj@tbzmed.ac.ir+98 41 3334 2178

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026