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The effect of Flaxseed and Nigella Sativa on MS

The effect of hydroalcoholic extracts of Flaxseed (seed of Linum usitatissimum) and Nigella Sativa plants on fatigue in MS patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140617018126N6
Enrollment
50
Registered
2022-11-01
Start date
2021-11-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigue of MS patients. Multiple sclerosis

Interventions

Intervention 1: Intervention group: This group will receive a capsule containing 0.75 ml Flaxseed and 0.75 ml Nigella Sativa soft gels every 12 hours and for 3 months. The capsules will be provided by

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with MS who had a stable condition for at least 8 weeks before entering the study The score and assessment of fatigue of the people included in the study by the tests should be higher than the minimum standards The psychotropic treatment regimens that the patients had before the start of the study should be adjusted for at least 4 weeks before the start of the study.

Exclusion criteria

Exclusion criteria: The patient has not had a relapse attack in the last 4 months The patient has not had an active infection in the last 4 months The patient has not received a corticosteroid pulse in the last 4 months. History of suicide attempts or suicidal thoughts

Design outcomes

Primary

MeasureTime frame
Fatigue in MS patients. Timepoint: MFIS questionnaire before taking and three months after taking drugs. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Araj-Khodaei

Tabriz University of Medical Sciences

araj@tbzmed.ac.ir+98 41 3334 2178

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026