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The effect of Lavandula Angustifolia, Echium amoenum, and Melissa officinalis in comparison with sertraline in the treatment of mild to moderate depression in older adults

Evaluation of the effect of Lavandula Angustifolia, Echium amoenum, and Melissa officinalis in comparison with sertraline in the treatment of mild to moderate depression in older adults: A triple-blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140617018126N5
Enrollment
120
Registered
2021-06-04
Start date
2021-08-23
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Other depressive episodes

Interventions

Intervention 1: Intervention group: This group will receive one capsule 250mg containing a combination of Lavandula Angustifolia (1 g) and Melissa officinalis (1 g) every 12 hours for two months. The

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 100 Years

Inclusion criteria

Inclusion criteria: Age over 60 years People referring to a psychiatrist with mild to moderate depression who have a depression score of 18 to 24 in the Hamilton questionnaire

Exclusion criteria

Exclusion criteria: No use of antidepressants and antipsychotics and mood-stabilizing nutrients four weeks before the clinical trial Having suicidal ideation Symptoms of major depression Alcohol use in the past 12 months Warfarin and phenytoin use People who have just started psychotherapy People who are pregnant and lactation Taking birth control pills Substance abuse Biological and physical factors such as head trauma, hypothyroidism, dementia, bipolar spectrum, and psychoses Receiving ECT

Design outcomes

Primary

MeasureTime frame
Depression. Timepoint: The first, second, fourth and eighth weeks. Method of measurement: Hamilton Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Araj-Khodaei

Tabriz University of Medical Sciences

araj@tbzmed.ac.ir+98 41 3334 2178

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026