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The effect of cerebrolysin versus placebo on improvement of patients with acute ischemic stroke

The effect of cerebrolysin versus placebo on improvement of patients with acute ischemic stroke: a double blinded randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201406169014N36
Enrollment
122
Registered
2014-06-23
Start date
2013-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ichemic stroke. cerebral infarction

Interventions

Routine treatment of ischemic stroke plus intravenous infusion of 100 ml normal saline alone daily for 7 days.
Intervention 1: Routine treatment of ischemic stroke plus intravenous infusion of cerebrolysin 10 ml in 100 ml normal saline daily for 7 days. Intervention 2: Routine treatment of ischemic stroke plus
Treatment - Drugs
Placebo
Routine treatment of ischemic stroke plus intravenous infusion of cerebrolysin 10 ml in 100 ml normal saline daily for 7 days

Sponsors

Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) having ischemic stroke; (b) age of 40 to 85 years; (c) referring the patient within less than 24 hours after stroke. Exclusion criteria: (a) being in coma; (b) having systolic blood pressure above 240 mmHg or diastolic blood pressure above 120 mmHg; (c) history of myocardial infarction or heart failure; (d) history of renal failure; (e) history of liver failure; (f) having severe dementia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Measuring motor function. Timepoint: before intervention and 3 and 7 days after intervention. Method of measurement: using Canadian Stroke Scale.

Secondary

MeasureTime frame
Measuring motor function. Timepoint: one month after intervention. Method of measurement: using Madified Ranking Scale.;Measuring motor function. Timepoint: one month after intervention. Method of measurement: using Bartel Index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSajedeh Nazari

Farshchian Hospital

sajed_nazari@yahoo.com+98 81 3264 0021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026