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Effect of misoprostol in labor induction in post-term pregnancies

A comparison of vaginal and oral dose of misoprostol for labor induction in post-term pregnancies

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014061412789N3
Enrollment
180
Registered
2014-09-15
Start date
2014-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Efficacy on induction of labor. Failed medical induction of labour

Interventions

Intervention 1: Labor induction performs in group 3 by 25 micro grams misoprostol vaginally (posterior fornix). Based on conditions every 6 hours for 4 doses repeated. Before repeating each dose, vagi
Treatment - Drugs
Labor induction performs in group 3 by 25 micro grams misoprostol vaginally (posterior fornix). Based on conditions every 6 hours for 4 doses repeated. Before repeating each dose, vaginal examination
Labor induction performs in group 1 by 100 micro grams misoprostol orally. Based on conditions every 6 hours for 4 doses repeated. Before repeating each dose, vaginal examination to determine Bishop s
Labor induction performs in group 2 by 50 micro grams misoprostol orally. Based on conditions every 6 hours for 4 doses repeated. Before repeating each dose, vaginal examination to determine Bishop sc

Sponsors

Vice Chancellor for Research, Kurdistan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Gestational age (GA) greater or equal to 40 weeks and 6 days with cephalic presentation and Bishop score greater than 4 and a height of 150 cm. Exclusion criteria included contraindications to receive misoprostol (allergies, asthma, Pelvic Inflammatory Disease, Acute Cerebrovascular Disease, Coronary Artery Disease, seizures) and also placenta previa , history of previous cesarean section or uterine surgery, Cephalopelvic Disproportion , Bishop score greater than 4, and abnormal vaginal bleeding.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Interval from induction to delivery. Timepoint: From induction to delivery every 1 hour. Method of measurement: Vaginal exam for evaluation of dilatation and effacement.

Secondary

MeasureTime frame
Fetal distress. Timepoint: At delivery time and 48 hours after that. Method of measurement: Based on the examination of the fetal heart rate and is determined by a specialist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoosan Mirza Mohammadi Sadegh

Kurdistan University of Medical Sciences

sumimo54@yahoo.com+98 87 1613 1336

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026