head trauma. Diffuse brain injury
Conditions
Interventions
Intervention 1: Intervention group 1: In this groups, the patients will be treated with received intravenous (IV) citicoline with a dosage of 0.5 gr/ twice a day(group B) and the treatment period will
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 60 Years
Inclusion criteria
Inclusion criteria: Traumatic Head concussion GCS lower or equal to 8 Hospitalized in ICU and Neurosurgery ward Age between 5 to 60 years
Exclusion criteria
Exclusion criteria: severe cognitive disorders severe systemic disorder penetrating or open skull trauma severe chest or lung trauma subdural or large epidoral hematoma requiring surgery younger than 5 or older than 60 years pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of consciousness in a patients. Timepoint: First 7 days and on 14th day of hospitalization. Method of measurement: Glasgow Coma Scale scoring system.;Muscle strength degree. Timepoint: The first week, on day 14, 21 and 30 of hospitalization. Method of measurement: Manual Muscle Testing scale.;Contusion volume and cerebral edema. Timepoint: Days 1, 3, 5 and 7. Method of measurement: Computed Tomography scans.;Length of dependency on a ventilator. Timepoint: 30 days of hospitalization. Method of measurement: Documentary Registry Data.;Stay length in the intensive care unit. Timepoint: 30 days of hospitalization. Method of measurement: Documentary Registry Data. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSoroush Hozeifi
Birjand University of Medical Sciences
Outcome results
None listed