The Comparison Effect Of ondansetron and Ginger on Postoperative Nausea And Vomiting after Ophthalmic Surgery

The Comparison Effect Of ondansetron and Ginger on Incidence and Severity of Postoperative Nausea and Vomiting in Patients Undertaken Ophthalmic Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014060918020N1

Enrollment

150

Registered

2014-07-02

Start date

2014-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Glaucoma. Condition 2: Paralytic strabismus. Condition 3: cataract. Glaucoma Paralytic strabismus capsular glaucoma with pseudoexfoliation of lens

Interventions

Intervention 1: Intervention 1: administration of ginger capsules contain 1000 mg drug with 30 cc water 1 hour before surgery. Intervention 2: Control: administration of placebo capsule with 30 cc wat

Treatment - Drugs

Intervention 1: administration of ginger capsules contain 1000 mg drug with 30 cc water 1 hour before surgery

Control: administration of placebo capsule with 30 cc water 1 hour before surgery

Intervention 2: administration of Ondansetron capsules contain 16 mg drug with 30 cc water 1 hour before surgery

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Lack of cancer; Age 18 to 60 years; Ability to swallow capsules used in the study; Platelet count above 100 thousand; Not suffering from intestinal obstruction and hepatitis; Not pregnant; Absence epilepsy, diabetes and kidney disease; Lack of anti-emetic drugs; Lack of long-term treatment with corticosteroids; No history of allergy to ginger or ondansetron Exclusion Criteria: Severe nausea and vomiting after surgery and require to use antisemitic

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausea. Timepoint: 2,4,6 hours after surgery. Method of measurement: Using a Check lists and standard tools.;Vomiting. Timepoint: 2,4,6 hours after surgery. Method of measurement: Using a Check lists and standard tools.	—

Secondary

Measure	Time frame
Cramp. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Heartburn. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Dyspenia. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Diarrhea. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Insomnia. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.	—

Measure

Time frame

Cramp. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Heartburn. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Dyspenia. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Diarrhea. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.;Insomnia. Timepoint: 2, 4, 6 hours after surgery. Method of measurement: Visual analysis and Scoring.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Moradi Majd

Iran University of Medical Sciences

moradimajd.p@gmail.com+98 21 8670 4727

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026