Condition 1: Purulent Endophthalmitis. Condition 2: Open globe injury. Panophthalmitis Vitreous abscess Penetrating wound of orbit with or without foreign body
Conditions
Interventions
Intervention 1: intervention group : oral Tablet of ciprofloxacin 500 mg twice a day for five days. Intervention 2: control group : Intravenous cefazolin 50 mg/kg four times a day and Intravenous gent
Treatment - Drugs
intervention group : oral Tablet of ciprofloxacin 500 mg twice a day for five days
control group : Intravenous cefazolin 50 mg/kg four times a day and Intravenous gentamicin 80 mg/kg three times a day for 3 days
Sponsors
Vice chancellor for research , Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria : The need for acute endophthalmitis prophylaxis ; living in Zahedan Exclusion criteria : All patients who have had eye surgery and other eye diseases ; single-eye patients ; patients who are undergoing medical treatment ; less than 18 years of age ; suspicion for fungal infection ; severe infection
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute endophthalmitis onset. Timepoint: one week. Method of measurement: examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral ciprofloxacin adverse effects. Timepoint: 1 week. Method of measurement: history and examination.;IV cefazolin and gentamicin adverse effects. Timepoint: 1 week. Method of measurement: history , examination and lab test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Hossein Validad
Zahedan University of Medical Sciences
Outcome results
None listed