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Atracurium and remifentanil on intubation conditions

The comparison of Atracurium and remifentanil effect on conditions of joint laxity and tracheal intubation without muscle relaxant in patients undergoing elective surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014060812642N2
Enrollment
66
Registered
2014-07-18
Start date
2014-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheal Intubation. Failed or difficult intubation

Interventions

Intervention 1: Intervention group:propofol 2.5 mg/kg IV before anaesthesia +Atropine 0.5 mg IV+Remifentanil 2 µg/kg IV. Intervention 2: Control group:propofol 2.5 mg/kg IV + Atropine 0.5 mg IV+Atracu
Treatment - Drugs
Intervention group:propofol 2.5 mg/kg IV before anaesthesia +Atropine 0.5 mg IV+Remifentanil 2 µg/kg IV
Control group:propofol 2.5 mg/kg IV + Atropine 0.5 mg IV+Atracurium 0.5 mg/kg

Sponsors

Vice Chancellor of Research of Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 139 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: candidate for elective surgery; Functional Class I Exclusion criteria: Mallampati score III or IV; chronic alcohol or opioid use; allergy to the study medications

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Vocal cord movement. Timepoint: 90 second after remifentanil and 180 second after atracurium administration. Method of measurement: anasthesiologist evaluation as close, with movement and open vocal cord.;Jaw relaxation. Timepoint: 90 second after remifentanil and 180 second after atracurium administration. Method of measurement: anasthesiologist evaluation as comfort, average and difficult.;Bucking. Timepoint: 90 second after remifentanil and 180 second after atracurium administration. Method of measurement: anasthesiologist evaluation as abdominal muscle, diaphragmatic and relax.

Secondary

MeasureTime frame
Bucking on tracheal tube. Timepoint: immidately after intubation. Method of measurement: presnce of cough.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026