Chemotherapy-induced mucositis. Other and unspecified lesions of oral mucosa
Conditions
Interventions
Intervention 1: Rinsing with normal saline (15 ml) followed by chlorhexidine 0.2% mouthwash (15 ml), 2 times a day (after breakfast and dinner) for 2 weeks. Intervention 2: Rinsing with persica oral d
Prevention
Rinsing with normal saline (15 ml) followed by chlorhexidine 0.2% mouthwash (15 ml), 2 times a day (after breakfast and dinner) for 2 weeks
Rinsing with persica oral drops (10 drops in 15 ml water) followed by chlorhexidine 0.2% mouthwash (15 ml), twice a day (after breakfast and dinner) for 2 weeks
Sponsors
Vice Chancellor for Research of Shahid Sadoughi University of Medical Sciences of Yazd
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age range of 6-12 years; history of hematologic malignancies with the same treatment protocol; no history of sensitivity to any substances; no history of asthma, allergic rhinitis and dermatitis; no need of radiotherapy; written informed consent obtained from parents or legal guardian. Exclusion criteria: occurrence of any infection; occurrence of sensitivity to mouth-rinses.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of mucositis. Timepoint: Day 1 (before intervention), 8 and 15. Method of measurement: World Health Organization (WHO) grading.;Severity of mucositis. Timepoint: Day 1 (before intervention), 8 and 15. Method of measurement: World Health Organization (WHO) grading; Oral Assessment Guide (OAG) grading. | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: Day 1 (before intervention), 8 and 15. Method of measurement: Facial Image Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Yasamin Khaksar
Dental Faculty of Shahid Sadoughi University of Medical Sciences of Yazd
Outcome results
None listed