Comparative evaluation of the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and Xylitol-containing chewing gum on salivary

Comparative evaluation of the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and Xylitol-containing chewing gum on salivary flow rate, pH and concentration of calcium and phosphate

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140601017935N8

Enrollment

Registered

2019-12-14

Start date

2019-12-21

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: chewing gum. Condition 2: chewing gum.

Interventions

Intervention 1: Intervention group:First Intervention group : First,They will brush twice daily for 3 weeks with a toothbrush(Medical) and toothpaste(Nasim). On the sampling day they will not eat anyt

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ????? 60 ??? ?? ????????? ????? ????? ????? ????? ???? ?? ???? ???????

Exclusion criteria

Exclusion criteria: ????? ???? ????? ??? ????? ????? ?? ???? ???? ????? ???? ???? ?????? ?? ???? ?????? ? ???? ??? ???? ???? ?? ???? ??? ?? ???? ?????? ???? ????? ??????? ?? ???? ???????? ? ????? ??????? ????? ??????? ????? ?????? ????????? ?????? ?? ??????? ???? ?????? ?????

Design outcomes

Primary

Measure	Time frame
Changes in salivary flow rate, pH and concentration of calcium and phosphate. Timepoint: Before the intervention, immediately after the intervention. Method of measurement: Salivary volume will be measured by calibrated pipette, salivary pH using a calibrated digital pH meter, salivary calcium spectrophotometric method, salivary phosphate will be measured spectrophotometric method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezoo Ghotbzade

Yazd University of Medical Sciences

arezoo.ghotbzade@yahoo.com+98 35 3625 5881

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026