The effect of tranexamic acid on blood loss during and after cesarean in women who candidate for cesarean section delivery

The effect of tranexamic acid on blood loss during and after cesarean in women who candidate for cesarean section delivery by clinical trial study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201405313485N4

Enrollment

Registered

2014-09-09

Start date

2014-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified. postpatrum-haemorrhage

Interventions

Intervention 1: Giving 1g intra venous tranexamic acid diluted with 20cc dextrose water 5% in 15min before skin incision. Intervention 2: Giving 1g intravenous distilled water as placebo diluted with

Treatment - Drugs

Giving 1g intra venous tranexamic acid diluted with 20cc dextrose water 5% in 15min before skin incision

Giving 1g intravenous distilled water as placebo diluted with 20cc dextrose water 5% in 15min before skin incision

Eligibility

Sex/Gender

Female

Age

135 Years to 137 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Primiparas and multiparas females with singleton pregnancy during the gestational ages of 37 to 40 weeks who are going to be delivered by cesarean section through fannenstiel’s incision and spinal anesthesia Non-inclusion criteria: Patients with problem of heart, liver and kidney; hematologic or rheumatologic problems; history of thyroid disease; abnormal placental; severe preeclampsia; macrosomia; severe anemia; problematic obstetric history Exclusion criteria: allergy to Tranexamic acid

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood loss during and two hours after surgery. Timepoint: During surgery until two hours. Method of measurement: Measuring the weight of bloody gauzes, pads and cloths during and two hours after the surgery and the amount of blood from the suction machine during the surgery.	—

Secondary

Measure	Time frame
The need of blood transfusion. Timepoint: To 48 hours after a cesarean section. Method of measurement: Checking of hemoglobin and hematocrit during 12 to 24 hours after the surgery and checking vital signs every 4 hours.;The need of hysterectomy. Timepoint: To 48 hours after a cesarean section. Method of measurement: Checking vital signs and examination for Atonic uterus and abnormal vaginal bleeding every 4 hours.	—

Measure

Time frame

The need of blood transfusion. Timepoint: To 48 hours after a cesarean section. Method of measurement: Checking of hemoglobin and hematocrit during 12 to 24 hours after the surgery and checking vital signs every 4 hours.;The need of hysterectomy. Timepoint: To 48 hours after a cesarean section. Method of measurement: Checking vital signs and examination for Atonic uterus and abnormal vaginal bleeding every 4 hours.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Forozan Milani

Guilan University of Medical Sciences

forozanmilani@yahoo.com+98 13 1322 5624

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026