Melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group: liposomal hydroquinone %4 was prescribed for one side of face once a day and also use of sunblock every 3 hours daily for 12 weeks. Intervention 2: Control group: c
Treatment - Drugs
Intervention group: liposomal hydroquinone %4 was prescribed for one side of face once a day and also use of sunblock every 3 hours daily for 12 weeks.
Control group: conventional topical hydroquinone %4 was prescribed for one side of face once a day and also use of sunblock every 3 hours daily for 12 weeks.
Sponsors
Vice Chancellor for research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Clinical Melasma; age over 18. Exclusion criteria: Pregnancy or breastfeeding; Infectious skin diseases; Simultaneous important medical conditions; Drug use (OCP, anticonvulsants, recent hormone therapy and Corticosteroids); Patients who used bleaching drug treatment in the last 4 months; Patients who had laser and IPL operations in the last 6 months; Patients who did not have follow ups at regular appointed times; In case of side effects.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease severity. Timepoint: once a month and one month after last visit. Method of measurement: Melasma area severity index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Faeze Golnouri
Mashhad University of Medical Sciences
Outcome results
None listed