Carpal tunnel syndrome. Carpal tunnel syndrome
Conditions
Interventions
Intervention 1: placebo:liquid paraffin, 5 drops, palmar wrist local use, morning and night-time, 4 weeks
with wrist splint with 5 degrees extension for night-time use. Intervention 2: drug: c
Placebo
Treatment - Drugs
placebo:liquid paraffin, 5 drops, palmar wrist local use, morning and night-time, 4 weeks
with wrist splint with 5 degrees extension for night-time use
drug: chamomile oil, 5 drops, palmar wrist local use, morning and night-time, 4 weeks
with wrist splint with 5 degrees extension for night-time use
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: primary idiopathic carpal tunnel syndrome; patients aged between 18-70 years old; electrodiagnostic criteria for mild or moderate CTS; Patient's written informed consent for inclusion; having at least two signs or one sign plus one symptom of: paresthesias, numbness, tingling, night pain positive Phalen test, positive Tinnel test, positive compression test. Exclusion criteria: Clinical and electrodiagnostic evidence of severe CTS including muscular atrophy and neurogenic changes in needle EMG of APB muscle; recurrent carpal tunnel syndrome; Positive history of trauma and/or fracture of wrist bones and/or surgical release of median nerve and/or direct injection into carpal tunnel of wrist; Evidence of cervical radiculopathy in EMG; Systemic disease including: neuropathies (rule out by nerve conduction study of ulnar nerves) and/or collagen vascular diseases such as SLE and scleroderma and RA; Endocrine diseases such as hypothyroidism and DM; Other disease-inducing neuropathy; Situations such as renal failure and/or alcoholism and/or poor medical condition; History of recent and ongoing use of corticosteroids or analgesics that could not be discontinued; hypersensitivity to the drug or placebo; inability to completion of data gathering forms (cognitive or language disorder).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Boston Carpal Tunnel Questionnaire score. Timepoint: beginning of the study and after 4 weeks. Method of measurement: Boston Carpal Tunnel Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Median nerve wrist sensory nerve conduction velocity. Timepoint: beginning of the study and after 4 weeks. Method of measurement: electrodiagnosis.;Median nerve sensory distal latency. Timepoint: beginning of the study and after 4 weeks. Method of measurement: electrodiagnosis.;Median nerve compound latency. Timepoint: beginning of the study and after 4 weeks. Method of measurement: electrodiagnosis.;Median nerve motor distal latency. Timepoint: beginning of the study and after 4 weeks. Method of measurement: electrodiagnosis.;Compound nerve action potential. Timepoint: beginning of the study and after 4 weeks. Method of measurement: electrodiagnosis.;Median nerve sensory proximal latency. Timepoint: beginning of the study and after 4 weeks. Method of measurement: electrodiagnosis.;Grip power. Timepoint: beginning of the study and after 4 weeks. Method of measurement: dynamometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Hashem Hashempur
Shiraz University of Medical Sciences
Outcome results
None listed