Acute haemorrhagic gastritis. Acute gastritis with bleeding
Conditions
Interventions
Intervention 1: Intervention group: Fibrinogen one gram diluted in 50 milliliters of distilled water. Fibrinogen manufactured by CSL Behring company in USA. In addition, the standard treatment of acut
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Having acute gastrointestinal bleeding At least 18 years old
Exclusion criteria
Exclusion criteria: Congenital diseases or acquired coagulation disorder Myocardial infarction two months ago History of gastrointestinal bleeding History of heart disease Fibrinogen sensitivity Pregnancy Cirrhosis Vasculitis The presence of any type of cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rebleeding. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Hemoglobin test.;The need for blood transfusion or its products. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Hemoglobin test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Observation and clinical examinations of the patient.;Administration in intensive care unit. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Administrated patients in the intensive care unit.;Need for endoscopy. Timepoint: 24 and 72 hours and 28 days after intervention. Method of measurement: Endoscopy performed in patients under study. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNader Tavakoli
Iran University of Medical Sciences
Outcome results
None listed