Antipyretic effect of intravenous ibuprofen compared to oral ibuprofen or rectal diclofenac in children

Antipyretic effect of intravenous ibuprofen compared to oral ibuprofen and rectal diclofenac in children

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014052711145N10

Enrollment

Registered

2014-08-12

Start date

2014-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever. Fever, unspecified

Interventions

Intervention 1: Ibuprofen, 5 mg/kg , intravenous, single dose at the initiation of fever control. Intervention 2: Ibuprofen, 5 mg/kg , oral, single dose at the initiation of fever control. Interventio

Treatment - Drugs

Ibuprofen, 5 mg/kg , intravenous, single dose at the initiation of fever control

Ibuprofen, 5 mg/kg , oral, single dose at the initiation of fever control

Diclofenac, 1 mg/kg , rectal, single dose at the initiation of fever control

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children admitted in Shahid Beheshti Hospital; axillary temperature over 38 degrees; aged 1 to 6 years. Exclusion criteria: The use of anti pyretic drug before admission; diarrhea; drug intolerance; using techniques such as sponge.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Axillary temperature. Timepoint: One hour after drug perception. Method of measurement: Mercury thermometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mohammad Reza Sharif

Kashan University of Medical Sciences

mrsharifmd@yahoo.com+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026