The Comparison of maxillary infiltration and mandibular block injection effect on the cardiovascular parameters with 2 different local anesthesia solutions

The comparative evaluation of maxillary infiltration and mandibular block injection effect on the cardiovascular parameters with 2 different local anesthesia solutions, Lidocaine and prilocaine in Patients Requiring Restorative Treatment of molar Teeth

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140527017880N6

Enrollment

112

Registered

2018-05-12

Start date

2018-05-20

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local anaesthetics. Local anaesthetics

Interventions

Intervention 1: Intervention group: Block injection in mandible with 1/8 milliliter of lidocaine 2% solution with epinephrine 1: 80,000 (Darou Pakhsh/iran). Intervention 2: Intervention group: infiltr

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: People aged 20-50 years Have general health needing restorative treatment of maxillary or mandibular molar teeth

Exclusion criteria

Exclusion criteria: Patients with medical history of cardiovascular, hypertension, Diabetes, kidney diseases, gastrointestinal bleeding or ulceration Use of medications that make disturbance in function of anesthetic substance Patients with pathology problems at the injection site pregnant and nursing patients

Design outcomes

Primary

Measure	Time frame
Level of systolic blood pressure. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: automatic brachial pressure gauge device.;Level of diastolic blood pressure. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: automatic brachial pressure gauge device.;Heart rate per minute. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: Finger pulse oximeter.;Peripheral blood oxygen saturation percentage. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: Finger pulse oximeter.	—

Measure

Time frame

Level of systolic blood pressure. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: automatic brachial pressure gauge device.;Level of diastolic blood pressure. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: automatic brachial pressure gauge device.;Heart rate per minute. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: Finger pulse oximeter.;Peripheral blood oxygen saturation percentage. Timepoint: 10 minutes before injection, immediately after injection, 10 minutes after injection, 20 minutes after injection. Method of measurement: Finger pulse oximeter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra lami

Kermanshah University of Medical Sciences

zahra.lami@yahoo.com+98 83 3722 2400

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026