type 2 diabetes. Insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group will consume probiotic soy milk containing 100000000 lactobacillus bacteria for 8 weeks. Intervention 2: control group: In this group soy milk without probiotic will
Prevention
Placebo
Intervention group will consume probiotic soy milk containing 100000000 lactobacillus bacteria for 8 weeks.
control group: In this group soy milk without probiotic will consume for 8 weeks
Sponsors
Isfahan University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patient with type 2 diabetes; between 25-75 years old; no consumption of vitamin supplement; antioxidants; mineral; omega-3 since 3 weeks ago. Exclusion criteria: smokers; pregnant and lactating women; patients with liver disease; IBS; thyroid disease; Rheumatoid arthritis; infection; heart diseases; sever infection; disobedience of recommended diet
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MLH1 promoter methylation. Timepoint: Before and after intervention. Method of measurement: MethyQESD method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum concentration of 8-Oxo-2'-deoxyguanosine. Timepoint: Before intervention and after eighth week. Method of measurement: Eliza method.;MSH2 promoter methylation. Timepoint: Before intervention and after eighth week. Method of measurement: methyQESD method.;The activity of superoxide reductase. Timepoint: Before intervention and after eighth week. Method of measurement: Eliza method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Ghiasvand
Isfahan University of Medical Sciences
Outcome results
None listed