Analgesic effect of paracetamol and meperidine after cesarean section.

Clinical trial of comparison between the effect of paracetamol (Apotel) and meperidine ( pethidine) on the pain in the first 24 hours after cesarean section.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201405262624N17

Enrollment

100

Registered

2015-04-25

Start date

2014-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean delivery. Single delivery by caesarean section

Interventions

Intervention 1: Intervention group: After finishing cesarean section and in the recovery room , pain of the patient has been determined using VAS . Then diclofenac suppository 100 milligram plus para

Treatment - Drugs

Intervention group: After finishing cesarean section and in the recovery room , pain of the patient has been determined using VAS . Then diclofenac suppository 100 milligram plus paracetamol ( Apotel

Control ( mepiridine) group: After finishing cesarean section and in the recovery room , pain of the patient has been determined using VAS . Then diclofenac suppository 100 milligram plus mepiridine (

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients after cesarean section with normal body mass index( between 18.5 and 25). Exclusion criteria: Drug abuse; history of allergy to paracetamol or mepiridine; history of hepatitis; renal failure; heart failure; respiratory disease;CNS disorders; coagulopathy; sedative use; psychiatric disorders and complication of cesarean section.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain . Timepoint: 0-1-2-4 and 6 hours after drug administration. Method of measurement: VAS.	—

Secondary

Measure	Time frame
Need to more analgesic. Timepoint: 0-1-2-4 and 6 hours after drug administration. Method of measurement: questionair.;Paracetamol adverse effects. Timepoint: 0-1-2-4 and 6 hours after drug administration. Method of measurement: VAS.;Side effects of meperidine. Timepoint: 0-1-2-4 and 6 hours after drug administration. Method of measurement: VAS.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Kashanian

Iran University of Medical Sciences

maryamkashanian@yahoo.com+98 21 5563 3244

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026