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Effects of acute stress on declarative memory reconsolidation across menstrual cycle

Effects of acute stress on declarative memory reconsolidation across menstrual cycle in healthy women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014052515975N1
Enrollment
56
Registered
2014-06-17
Start date
2013-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress. Stress, not elsewhere classified

Interventions

Intervention 1: In stress condition, participants expose to the socially evaluated cold pressor test (SECPT). Subjects will ask to immerse their right hand up to and including the wrist into ice water
On day 1, participants learn 30 pictures include ten positive pictures (such as Ice cream), ten negative pictures (example Injury) and ten neutral pictures(glass). Day2: Reactivation
On day 2, participants in reactivation group would be asked to remind the pictures they had learned on the previous day. In no reactivation group, participants reading newspaper. Immediately, they are
On day 3, participants would be asked to write down the pictures they had learned on day 1. Cued recall will be assessed immediately after free recall. After 2 months, participants return for days 4,
In stress condition, participants expose to the socially evaluated cold pressor test (SECPT). Subjects will ask to immerse their right hand up to and including the wrist into ice water (0-2 C). Subjec
Memory Task. Day1: Learning

Sponsors

Semnan University of Medical Sciences, Semnan, Iran
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 25 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Age between 18 and 25 years; Body mass index (BMI) between 19 and 26 kg/m2; No smoking; No addiction to narcotic substance and alcohol; No reported history of disease or psychiatric problems; No medication intake; No use of psychotropic drugs; No history of disease or abnormal laboratory test; Not being in stressful situations; Having a positive mood (According to PANAS); Naturally cycling with menstrual cycles between 24 and 32 days; Consent to participate in the study. Exclusion Criteria: Being in stressful situations or disease during study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Memory retrieval. Timepoint: Day 3. Method of measurement: Number of recalled pictures.

Secondary

MeasureTime frame
Salivary cortisol level. Timepoint: S1: Day 2, Before SECPT or Control condition (Base); S2: Day 2, 10 minutes after SECPT or Control ; S3: Day 2, 25 minutes after SECPT or Control; S4: Day 2, 60 minutes after SECPT or Control; S5: Day 3, Before retrieval test. Method of measurement: Immunoassay- IBL kit (IBL Immuno Biological Laboratories, Hamburg, Germany).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohsen Pourazizi

Semnan University of Medical Sciences

m.pourazizi@yahoo.com ; m.pourazizi@sem-ums.ac.ir+98 23 1335 4359

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026