Nausea & vomiting in pregnancy. Vomiting of pregnancy, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Treatment of one group with bitter orange. Intervention 2: Intervention group: The other group with ondansetron.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: gestational age between 6-20 weeks of pregnancy (according to a reliable LMP and ultrasound confirmation of the first trimester) Having mild to moderate nausea and vomiting without a need of hospitalization Singleton pregnancy with a live normal fetus Not having any known gastrointestinal disorder Without a history of smoking or drug use Lack of a known mental illness such as severe anxiety and depression Not having any known allergy or hypersensitivity to herbal medications
Exclusion criteria
Exclusion criteria: Severe nausea and vomiting needing hospitalization No acceptance for herbal medicine Having any other symptoms showing pathologic problems such as diarrhea Having any known gastrointestinal or any other systemic disorder or any drug use except common supplementation (folic acid)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of nausea and vomiting. Timepoint: Before start and two weeks later of treatment. Method of measurement: Visual analog scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score. Timepoint: Before start and two weeks later of treatment. Method of measurement: Short Form 36 Health Survey (SF-36). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarrokh khani
Shiraz University of Medical Sciences
Outcome results
None listed