Disorders of gallbladder, biliary tract and pancreas. Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
Conditions
Interventions
Intervention 1: Ketamine group will receive a loading dose of Ketamine 0.5 mg/Kg body weight intravenously over 60 seconds and then Fentanyl 1 mcg/Kg body weight intravenously. According to sedation l
Treatment - Drugs
Ketamine group will receive a loading dose of Ketamine 0.5 mg/Kg body weight intravenously over 60 seconds and then Fentanyl 1 mcg/Kg body weight intravenously. According to sedation level, in Ramsay
Propofol group will receive Propofol l mg/Kg body weight intravenously over 60 seconds and then Remifentanil 0.05 mcg/Kg body weight/min intravenously. Intravenous infusion of propofol will be maintai
Sponsors
Isfahan university of medical sciences, faculty of medicine
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Patient at age between 25 to 70 years; ASA physical status I and II; Patients without anatomic airway abnormalities; Patients without severe cardiovascular and respiratory disease; Patients without severe psychological problem; Patients who are not pregnant; Patients who are not smoker or addict; Patients without history of previous ERCP. Exclusion criteria: Occurring severe ERCP complications such as perforation and bleeding; ERCP procedural failure; Changing the sedation plan to the general anesthesia.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation level. Timepoint: every 5 min during the first 15 min of the procedure and then every 15 min until the end of procedure. Method of measurement: Ramsay scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dose repeats. Timepoint: during ERCP. Method of measurement: Questionnaire.;Recovery time. Timepoint: after procedure. Method of measurement: Aldrete score.;Systolic blood pressure. Timepoint: before the intervention then every 5 min during the first 15 min of the procedure and then every 15 min until the end of procedure and then at the entrance to the recovery room and after first 15 min. Method of measurement: sphygmomanomete.;Heart rate. Timepoint: before the intervention then every 5 min during the first 15 min of the procedure and then every 15 min until the end of procedure and then at the entrance to the recovery room and after first 15 min. Method of measurement: Beat/minute.;O2 saturation. Timepoint: before the intervention then every 5 min during the first 15 min of the procedure and then every 15 min until the end of procedure and then at the entrance to the recovery room and after first 15 min. Method of measurement: Pulse oximetry.;Respiratory rate. Timepoint: before the intervention then every 5 min during the first 15 min of the procedure and then every 15 min until the end of procedure and then at the entrance to the recovery room and after first 15 min. Method of measurement: per minute.;Retching. Timepoint: during ERCP. Method of measurement: Questionnaire.;Apnea occurrence. Timepoint: during ERCP. Method of measurement: Questionnaire.;Patient’s pain intensity. Timepoint: at 60 min post procedure. Method of measurement: Visual analogue scale(VAS).;Patient’s satisfaction. Timepoint: after procedure. Method of measurement: Visual analogue scale(VAS).;Intensity of nausea. Timepoint: at 60 min post procedure. Method of measurement: Visual analogue scale(VAS).;Endoscopist’s satisfaction. Timepoint: after procedure. Method of measurement: Visual analogue scale(VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSayed Morteza Heidari - Anaesthesiologist
Alzahra Hospital
Outcome results
None listed