Tuberculosis. Tuberculosis of lung, confirmed by sputum microscopy with or without culture
Conditions
Interventions
Intervention 1: 2. The intervention group will be treated with a combination of Anti-TB drug and whit a fixed dose that contains Rifampicin 8-12 mg per kg body weight, Isoniazid 4-6 mg per kg body wei
Treatment - Drugs
2. The intervention group will be treated with a combination of Anti-TB drug and whit a fixed dose that contains Rifampicin 8-12 mg per kg body weight, Isoniazid 4-6 mg per kg body weight, Pyrazinamid
3.The control group will be treated with the separate Anti-TB drug regimen that contains Rifampicin 8-12 mg per kg body weight, Isoniazid 4-6 mg per kg body weight, Pyrazinamide 20-30 mg per kg body w
Sponsors
vice chancellor for research, Urmia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
13 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: New cases of sputum smear positive; Patient weight more than 30kg; Adult (greater than13 years); No disease - diabetes, immune deficiency, liver or kidney disease; Informed consent. Exclusion Criteria: Smear-negative tuberculosis patients; Patients with a history of anti-TB medication use; Children younger than 13 years; Patients weighing less than 30 kg; Tuberculosis patients with diabetes, immune deficiency, liver or kidney disease; Lack of consent to participate in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sputum conversion rate. Timepoint: 2 , 3 and 6 month after Starting Treatment. Method of measurement: sputum smear status is investigated by optical microscope at the end of the second, third and sixth months of treatment and the result are registered in the checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFallah Saeid
Urmia University of Medical Sciences
Outcome results
None listed