A comparison of the effects of St. Thomas cardioplegia solutions on coronary sinus lactate

A comparative study of the effects of St. Thomas No. 1 and St. Thomas No. 2 cardioplegia solutions on coronary sinus lactate in mitral valve surgery patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140519017756N47

Enrollment

Registered

2021-12-27

Start date

2022-01-10

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mitral valve surgery. Nonrheumatic mitral (valve) prolapse

Interventions

Intervention 1: Intervention Group 1 (St. Thomas No. 1): Patients are injected with 10 cc/kg St. Thomas No. 1 Cardioplegia Cold Solution at 8 °C for three minutes through the antegrade approach. Inter

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Candidate for mitral valve replacement Age over 20 years Informed written consent

Exclusion criteria

Exclusion criteria: History of heart failure History of myocardial infarction Simultaneous operation of 2 or 3 valves Mitral valve reoperation Patients with EF <40%

Design outcomes

Primary

Measure	Time frame
Lactate level. Timepoint: 0, 15, and 30 minutes after applying the cross-clamp. Method of measurement: GEM premier model 5700.;Blood gases. Timepoint: 0, 15, and 30 minutes after applying the cross-clamp. Method of measurement: GEM premier model 5700.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Araki

Mashhad University of Medical Sciences

arkim1@mums.ac.ir+98 51 3180 2307

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026