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The therapeutic effects of garlic and ginger in workers exposed to lead

A clinical trial comparing the impact of garlic, ginger, and placebo on serum lead levels and some hematologic and serologic factors in workers exposed to lead

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140519017756N43
Enrollment
105
Registered
2018-05-05
Start date
2018-03-21
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lead poisoning. Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances

Interventions

Intervention 1: Intervention Group 1 (Garlic): For a period of four weeks, the garlic group will take three 400 milligram odorless garlic capsules after meals on a daily basis. Intervention 2: Interve

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Persons with a minimum of one-year tenure in occupations that have exposure to lead Informed consent to participate in study

Exclusion criteria

Exclusion criteria: Serum lead levels lower than 5 micrograms per deciliter serum lead levels above the therapeutic level Drug therapy to decrease lead blood level over the past six months History of allergy to garlic or ginger, as well as history of gastrointestinal ulcer, gallstones, asthma, and opiate addiction Being treated with aspirin and other anticoagulants or hypoglycemic agents for liver and kidney disease

Design outcomes

Primary

MeasureTime frame
Lead serum level. Timepoint: Before and after intervention. Method of measurement: atomic absorption device (PG Instrument Company, UK).

Secondary

MeasureTime frame
AST (Liver parameter). Timepoint: Before and after intervention. Method of measurement: laboratory test.;Urea. Timepoint: Before and after intervention. Method of measurement: laboratory test.;Hematologic parameters. Timepoint: Before and after intervention. Method of measurement: laboratory test.;ALT (Liver parameter). Timepoint: Before and after intervention. Method of measurement: laboratory test.;Creatinine. Timepoint: Before and after intervention. Method of measurement: laboratory test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSareh Nakhaei

Birjand University of Medical Sciences

nakhaee67@bums.ac.ir+98 56 3238 1411

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026