Effects of exercises on balance and falls in patients with multiple sclerosis

Effects of perturbation-based balance training versus traditional balance training on balance and risk of falling in people with multiple sclerosis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20140519017752N2

Enrollment

Registered

2018-10-31

Start date

2018-11-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group: receive walking and balance exercises with perturbation

Participants received 20-minute individualized (1 trainer to 1 participant) training sessions, 3 times a week for 4 weeks. Intervention 2: Control group: receive walking and balance exercises without

Participants received 20-minute individualized (1 trainer to 1 participant) training sessions, 3 times a week for 4 weeks.

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: A definite diagnosis of MS, relapsing-remitting or secondary progressive types, as diagnosed by a neurologist; History of falls in past 3 months; Ability to stand independently; Ability to walk independently at least for 100 meters; Ages between 18-64 years; MMSE more than 24; EDSS below 5/5 Exclusion criteria: Experiencing an exacerbation of symptoms due to relapse within 3 months of the baseline measurement; Any musculoskeletal or neurological conditions except MS limiting balance or gait; Uncorrected Auditory or visual impairment; Pregnancy; Involving in the other planned treatment; Receiving treatments to improve balance in past 3 months

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Static Balance. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Force plate.;Ability to adapt to unexpected changes in orientation of the support surface. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: "Adaptation test" in Computerized Dynamic Posturography system (Neurocom).;Effectiveness of the patient’s automatic motor responses to external perturbation. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: "Motor Control test" in Computerized Dynamic Posturography system (Neurocom).;Dynamic balance. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Time Up and Go Test, 10 meter walk test.;Functional balance. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Berg balance scale.;Balance confidence. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Activities Specific Balance Confidence scale.;Fear of fall. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Fall Efficacy Scale – International.;Fall rate. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Fall diary.	—

Measure

Time frame

Static Balance. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Force plate.;Ability to adapt to unexpected changes in orientation of the support surface. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: "Adaptation test" in Computerized Dynamic Posturography system (Neurocom).;Effectiveness of the patient’s automatic motor responses to external perturbation. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: "Motor Control test" in Computerized Dynamic Posturography system (Neurocom).;Dynamic balance. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Time Up and Go Test, 10 meter walk test.;Functional balance. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Berg balance scale.;Balance confidence. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Activities Specific Balance Confidence scale.;Fear of fall. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Fall Efficacy Scale – International.;Fall rate. Timepoint: Before and after intervention (at the end of 4th week). Method of measurement: Fall diary.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeideh Monjezi

Ahvaz University of Medical Sciences

saeideh.monjezi@yahoo.com+98 61 1374 3101

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026