Effect of levothyroxine on serum lipids in patients with subclinical hypothyroidism

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014051417686N1

Enrollment

Registered

2014-08-29

Start date

2013-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothyroidism. Subclinical iodine-deficiency hypothyroidism

Interventions

Intervention 1: In the case group Levothyroxine sodium (brand name Levoxin) tablet manufactured by Iran hormone pharmaceutical company with dose of 50 microgramg is used once a day for 3 months. Inte

Treatment - Drugs

In the case group Levothyroxine sodium (brand name Levoxin) tablet manufactured by Iran hormone pharmaceutical company with dose of 50 microgramg is used once a day for 3 months

No intervention is done in control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria:subclinical hypothyroidism; Exclusion criteris: TSH>10 mIU/L; pregnancy; hyperlipidemia; serum anti-TPO Ab positivity; goiter; diabetes mellitus; ischemic heart disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
LDL. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.;HDL. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.;TG. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.;TSH. Timepoint: 0 and 3 months later. Method of measurement: mIU/L.;T4. Timepoint: 0 and 3 months later. Method of measurement: ng/dL.;Cholesterol. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.	—

Measure

Time frame

LDL. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.;HDL. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.;TG. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.;TSH. Timepoint: 0 and 3 months later. Method of measurement: mIU/L.;T4. Timepoint: 0 and 3 months later. Method of measurement: ng/dL.;Cholesterol. Timepoint: 0 and 3 months later. Method of measurement: mg/dL.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahmoud Parham

Qom University of Medical Sciences

drparham@muq.ac.ir+98 25 3612 2952

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026