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Randomized, clinical trial to evaluate the effects of aloe vera mouthwash in comparison with non-alcoholic chlorhexidine on periodontal disease .

Evaluate and compare the efficacy of aloe Vera mouthwash with non- alcoholic Chlorhexidine mouthwash on periodontal diseases.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014051017587N5
Enrollment
24
Registered
2014-08-15
Start date
2014-07-18
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal diseases. Periodontal diseases

Interventions

Intervention 1: "Group A: mouthwash aloe Vera (Alodent Co. UK) for each patient, 10 ml by patients routinely washed two times in one day for about 30 seconds for two weeks.". Intervention 2: "Group B:
Treatment - Drugs
"Group A: mouthwash aloe Vera (Alodent Co. UK) for each patient, 10 ml by patients routinely washed two times in one day for about 30 seconds for two weeks."
"Group B: Non-alcoholic chlorexidine (Livar CO. SPAIN) for each patient,10 ml by patients routinely washed two times in one day for about 30 seconds for two weeks."

Sponsors

Deputy of Research Council Of Dental Branch, Islamic Azad University of Tehran
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Presence of two periodontal sites located on the same side pocket depth 4 mm or more, Chronic periodontitis patients. Exclusion criteria: Orthodontic treatment, Use removal denture. Presence of vertical bone defect, Use of medicine therapy within the 3 months prior to the study, Allergy to chlorhexidine and Aloe Vera, smoking. Systemic diseases that could influence the course of periodontal disease, Pregnancy and lactation, Aggressive periodontitis, Furcation involvement, Periodontal therapy 6 months prior to the study, Extensive caries.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduction of pocket depth. Timepoint: 7days. Method of measurement: Periodontal pobe.

Secondary

MeasureTime frame
Reduction of bleeding on probing. Timepoint: 7 days. Method of measurement: Periodontal probe.;Reduction of plaque index. Timepoint: 7 days. Method of measurement: Plaque Index(O’Leary ).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhossein Farahmand

Dental Branch, Islamic Azad University of Tehran

perio-implant@hotmail.com+98 21 2284 9604

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026