Skip to content

Randomized, double blind, placebo controlled clinical trial of compare with Doxycycline plus ketoprofen gel in Chronic Periodontitis

Efficacy of subgingivally delivered Doxycycline plus ketoprofen gel as an adjunct to non-surgical treatment of chronic Periodontitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014050717587N2
Enrollment
20
Registered
2014-06-23
Start date
2012-06-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal diseases. Periodontal diseases

Interventions

Intervention 1: ketoprofen gel ( 2.5% Sanofi Pharmaceutical plant construction in France ) + 3 % doxycycline (Kharzmai Pharmaceutical manufacture in Iran ) which be put into the periodontal pocket usi
Treatment - Drugs
ketoprofen gel ( 2.5% Sanofi Pharmaceutical plant construction in France ) + 3 % doxycycline (Kharzmai Pharmaceutical manufacture in Iran ) which be put into the periodontal pocket using an insulin sy
ketoprofen gel ( 2.5% Sanofi Pharmaceutical plant construction in France), which be inserted into the periodontal pocket using an insulin syringe .

Sponsors

Deputy of Research Council of Dental Branch Islamic Azad University of Tehran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: adult patients, older than 18 years old, systemically healthy, and having at least 20 teeth. Exclusion criteria: patients with cavitated caries, no periodontal pockets larger than 4 mm, orthodontic appliances or removable prostheses, allergies to cetylpyridinium or CHX, use of antibiotics and anti-inflammatory drugs in the past 3 months that might alter normal gingival health, oral prophylaxis outside of study; use of oral chlorhexidine products or participation in an oral rinse study within 3 months prior to baseline examination, pregnancy or lactation, smoking.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduction of pocket depth. Timepoint: 15 Days. Method of measurement: Periodontal probe.

Secondary

MeasureTime frame
Reduction of bleeding on probing. Timepoint: 15 Days. Method of measurement: Periodontal probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhossein Farahmand

Dental Branch Islamic Azad University of Tehran

perio-implant@hotmail.com+98 21 2284 9604

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026