Condition 1: vulvitis and vulvovaginal candida. Condition 2: bacterial vaginosise. Candidiasis of vulva and vagina inflammation of vagina and vulva
Conditions
Interventions
Intervention 1: Vaginal probiotic capsules containing Lactobacillus rhamnosus 10 ^ 9 colony is known to be vaginally twice a day for seven days. Intervention 2: Vaginal placebo capsule form twice a da
Treatment - Drugs
Placebo
Vaginal probiotic capsules containing Lactobacillus rhamnosus 10 ^ 9 colony is known to be vaginally twice a day for seven days
Vaginal placebo capsule form twice a day for seven days
Sponsors
Vice chancellor for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : aged 18 to 40 years ; Married ; nonpregnant ; willing to participate in research ; suffering from bacterial vaginosis or Vulvovaginal Candidiasis (according to the criteria of Amsel and culture test fungi ) ; having menstrual natural ? nonsmokers ; not suffering from diseases such as liver disease heart , kidney, diabetes , Sbby system diseases , immune deficiency , sexually transmitted diseases, abnormal vaginal bleeding ; lack of non-use of broad-spectrum antibiotics , hormones ( such as birth control pills ) , alcohol , drugs anticoagulant and immunosuppressive drugs during the past month ; lack of sexual intercourse during the last 48 hours of non-use vaginal medicines within the last 48 hours last 48 hours ; lack of vaginal washings or not sensitive to clindamycin clotrimazole during pregnancy Exclusion Criteria : allergies symptoms, allergy to clindamycin or clotrimazole vaginal probiotic or placebo ; Getting pregnant
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cultivated candida. Timepoint: 2-5 days after initial treatment,2-5 days after and one month after the use of probiotics or placebo. Method of measurement: Cultivate.;Amsel criteria. Timepoint: 5-2 days after initial treatment,2-5 days after and one month after the use of probiotics or placebo. Method of measurement: Discharge, vaginal PH measurements,Whiff test, see clue cells under the microscope.;Cultures of vaginal lactobacilli. Timepoint: 2-5days after initial treatment,2-5 days after and one month after the use of probiotics or placebo. Method of measurement: Cultures of vaginal lactobacilli. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reacton to probiotics - clindamycin -clotrimazole. Timepoint: During the entire study. Method of measurement: The patient complained. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactsara Azima
Fatemeh (PBUH) College of Nursing and Midwifery
Outcome results
None listed