Evaluation the effect of Propofol, Etomidate, and Sodium Thiopental on depth of Anesthesia and duration of Seizure in the electroconvulsive therapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014050617602N1

Enrollment

132

Registered

2014-05-20

Start date

2014-09-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electroconvulsive Therapy. Treatment of depressive episode

Interventions

Treatment - Drugs

Intervention 1: Propofol: Dose: 2 mg/kg Number of using: Once Factory name: Astra Zeneca Manufacturing Country's Name: India Location prescribed: Intravascular Administration time: At the beginn

Propofol: Dose: 2 mg/kg Number of using: Once Factory name: Astra Zeneca Manufacturing Country's Name: India Location prescribed: Intravascular Administration time: At the beginning of the

Etomidate: Dose: 0.4 mg/kg Number of using: Once Factory name: Janssen Cilag Manufacturing Country's name: England Location prescribed: Intravascular Administration time: At the beginning of

Sodium Thiopental: - Dose: 5 mg/kg - Number of using: Once - Factory name: Jubilant - Manufacturing Country's name: India - Location prescribed: Intravascular - Administration time: At the

Eligibility

Sex/Gender

All

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Admitted patients for Electroconvulsive Therapy in Golestan hospital; 30 to 50 years old; Anesthesia risk of 1, 2 (According to American society of anesthesiologist's classification). Exclusion criteria: Patient refuse; Under 30 and over 50 years old; A history of drug abuse; Sensitivity to egg; Contraindication of Propofol, Etomidate or Sodium Thiopental.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Measuring Depth of Anesthesia. Timepoint: Continuously during procedure. Method of measurement: By bipolar electroencephalographic leads that connected to the temporal and frontal area of patients and brain waves evaluated by BIS monitoring according to numbers from 0 to 100.;Duration of Seizure. Timepoint: After procedure. Method of measurement: Clinical Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZohre Fadaei

Ahvaz Jundishapur University of Medical Sciences

fadaei.z@ajums.ac.ir, mostafafatahi777@gmail.com+98 61 1658 9657

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026