Comparison of the effects of heparin and 0.9% sodium chloride solutions in maintenance of patency of central venous catheters

Comparison of the effects of heparin and 0.9% sodium chloride solutions in maintenance of patency of central venous catheters in intensive care unite

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014050613156N5

Enrollment

Registered

2014-05-17

Start date

2014-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CVA. G90.3

Interventions

Intervention 1: Heparin group: In the heparin group patient's solution will be prepared by a 1000 unit heparin ampoule will being added to half a liter normal saline and so each milliliter of the prep

Treatment - Drugs

Treatment - Other

Heparin group: In the heparin group patient's solution will be prepared by a 1000 unit heparin ampoule will being added to half a liter normal saline and so each milliliter of the prepared solution wi

Normal salin group: In normal saline group patients 10mL 0.9% sodium chloride was injected in each lumen of the catheter. Method will be done acording heparin group

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 18-60 years old; time passed from insertion of the catheter would be less than 12 hours; usage of triple lumen silicone catheters; patient’s blood platelet of 150000-450000; PT of 11-12.5 seconds; PTT in the range of 35-45 seconds and having received 1 liter of serum KVO during 24 hours Exclusion criteria: risk of bleeding; receiving blood products during study and an increase in body temperature higher than 37.7 C.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Maintenance of patency of central venous catheters. Timepoint: Each 8 hours for 21 days. Method of measurement: Chek list.	—

Secondary

Measure	Time frame
Hemoraghia. Timepoint: Each 8 hour for 21 days. Method of measurement: Chek list.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Ali Heydarigorji

Mazandaran University of Medical Sciences

heydarigorji@yahoo.com+98 15 1226 7342

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026