The effect of moderate hypothermia on the dosage of anesthetic medication and recall of anesthesia

Comparing the effect of moderate hypothermia and normothermia on the dosage of anesthetic medication and recall of anesthesia in ?drug-addicted patients undergoing coronary artery bypass surgery.?

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014050513159N5

Enrollment

Registered

2014-06-23

Start date

2014-05-03

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

investigation of effect of anesthesia drug consumption ?. Other complications of anaesthesia

Interventions

Intervention 1: Intervention group: Hypothermic condition, after aortic cannulation by cardiopulmonary bypass pump, body is slowly cooled till (28-32 ° C). Intervention 2: Control group: normothermic

Diagnosis

Intervention group: Hypothermic condition, after aortic cannulation by cardiopulmonary bypass pump, body is slowly cooled till (28-32 ° C)

Control group: normothermic condition, At the end of surgery patient's body temperature is warmed till (36 Centigrade) by blanket under patient

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: The major inclusion criteria: Patients between 30 and 70 years old with opium addiction who are candidate for elective coronary ?bypass on-pump surgery. The major exclusion criteria: History of previous anesthesia for cardiac surgery; ASA Physical Status Classification System more than 4, History of alcohol ?consumption; History of addiction to opium; History of long-term use of psychotropic drugs or tranquilizers.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The total amount of medication (Fentanyl and Propofol) to achieve the desired depth of anesthesia. Timepoint: During surgery and at the time of extubation after surgery. Method of measurement: Clinical check list by researchers and the bispectral Index monitor.;Awareness during anesthesia. Timepoint: 24 hour after extubation. Method of measurement: Questionnaire ?with open questions.;Depth of anesthesia (40-60). Timepoint: During surgery and at the time of extubation after surgery. Method of measurement: The bispectral Index monitor.;The total amount of extra medication (Fentanyl and Propofol) to achieve the desired depth of anesthesia. Timepoint: During surgery and at the time of extubation after surgery. Method of measurement: Clinical check list by researchers.	—

Measure

Time frame

The total amount of medication (Fentanyl and Propofol) to achieve the desired depth of anesthesia. Timepoint: During surgery and at the time of extubation after surgery. Method of measurement: Clinical check list by researchers and the bispectral Index monitor.;Awareness during anesthesia. Timepoint: 24 hour after extubation. Method of measurement: Questionnaire ?with open questions.;Depth of anesthesia (40-60). Timepoint: During surgery and at the time of extubation after surgery. Method of measurement: The bispectral Index monitor.;The total amount of extra medication (Fentanyl and Propofol) to achieve the desired depth of anesthesia. Timepoint: During surgery and at the time of extubation after surgery. Method of measurement: Clinical check list by researchers.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Sheybani

Mashhad University of Medical Sciences

sheybanish@mums.ac.ir+98 51 1801 2612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 12, 2026