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The Effect of Angiotensin Convetring Enzyme Inhibitor on the Quality of Life of Non Hospitalized Patients With Cancer Cachexia in Shiraz University Clinics

The Effect of Angiotensin Converting Enzyme Inhibitor on the Quality of Life of Non Hospitalized Patients With Cancer Cachexia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014050511375N3
Enrollment
40
Registered
2014-10-23
Start date
2013-10-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer. Malignant neoplasm of stomach

Interventions

Intervention 1: Intervention group will be administrated Captopril. Intervention 2: Control group will be received placebo (starch pill).
Treatment - Drugs
Placebo
Intervention group will be administrated Captopril
Control group will be received placebo (starch pill)

Sponsors

Shiraz University of Midical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Patients with aged 40-80 years old; Patients with BMI less 18 and those with muscle wasting or only temporal wasting. Exclusion Criteria: Patients unable to continue the treatment; Patients with BMI more 18 without temporal or muscle wasting; Those with GFR less 50 ml/min; Positive history of other co-morbidity diseases; Patients with Hb less 9; Patients unavailable for or incapable of filling out questionnaires at different intervals.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Body Mass Index. Timepoint: Bfore and 1 month and 2 months after intervention. Method of measurement: By BMI Formula.

Primary

MeasureTime frame
Quality of life. Timepoint: Before and 1 month and 2 months after intervention. Method of measurement: QLQ-C30 questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mehdi Mirzaei

Shiraz University of Medical Sciences

Mirzaeim@sums.ac.ir+98 71 1234 3529

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026