Condition 1: Neurasthenia, Malaise and fatigue. Condition 2: Multiple Sclerosis. Neurasthenia, Malaise and fatigue Multiple sclerosis
Conditions
Interventions
Intervention 1: In intervention group: Using product (majoone badaam) with 15 grams daily dose, orally, divided into three times: fasting, one hour before lunch, one and half to two hrs after lunch o
Treatment - Drugs
Placebo
In intervention group: Using product (majoone badaam) with 15 grams daily dose, orally, divided into three times: fasting, one hour before lunch, one and half to two hrs after lunch over four weeks.
In control group: Using placebo with 15 grams daily dose, orally, divided into three times: fasting, one hour before lunch, one and half to two hrs after lunch over four weeks
Sponsors
Vice Chancellor for Research of Faculty of Traditional Iranian Medicine of Tehran University of Medi
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: MS diagnosis, either relapsing remitting (RR) secondary progressive (SP) or primary progressive, based on specified criteria of modern medicine by MC.Donald criterion approved with neurologist; MS-related fatigue lasting at least one month and there should be indication of anti fatigue treatment; consciously accepting subscription form/ letter of satisfaction; patient shouldn't be under simultaneous anti-fatigue medical treatment; not using any other natural or herbal treatment by the patient during the study; lack of any record of sensitivity to drug ingredients; EDSS equal or less than 6; MFIS more than 45; no crisis of disease over the previous 60 days and Exclusion criteria: relapse of disease over the study period; uncontrolled diabetes; blood hypertension; pregnant or lactating mothers; severe infection; severe mental disorders
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Fatigue Impact Scale (MFIS) Standard Questionnaire. Timepoint: Before intervention and after four weeks. Method of measurement: Filling out Modified Fatigue Impact Scale (MFIS) Standard Questionnaire by the patient.;Visual Analog Scale (VAS) for Fatigue. Timepoint: Before intervention and after four weeks. Method of measurement: Filling out Visual Analog Scale (VAS) by the patient. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Quality of patients contributed in the study. Timepoint: Before intervention and after four weeks. Method of measurement: Filling out Pittsburgh Sleep Quality Index (PSQI) by the patient.;Constipation in patient. Timepoint: Before intervention and after four weeks. Method of measurement: Filling out Rome III Criteria for constipation module by the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Bagher Minae
Tehran University of Medical Sciences
Outcome results
None listed