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Effect of HCG (human chorionic gonadotropin) injection on clinical pregnancy in ART (Assisted Reproductive Technology) cycles

compairig the efficacy of intramuscular injection of HCG(human chorionic gonadotropin )before embryo transfer versus intrauterine injection with control group on clinical pregnancy in infertile women canditate for ART (Assisted Reproductive Technology)cycle

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014050316912N2
Enrollment
200
Registered
2014-11-23
Start date
2014-08-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. female infertility associated with male factor

Interventions

Intervention 1: The day of embryo transfer, 1500 IU hcG (human chorionic gonadotropin) will be injected intermuscular in one group. Intervention 2: The day of embryo transfer, 500 IU hcG (human chorio
Treatment - Drugs
The day of embryo transfer, 1500 IU hcG (human chorionic gonadotropin) will be injected intermuscular in one group
The day of embryo transfer, 500 IU hcG (human chorionic gonadotropin) will be injected 7 minutes before embryo transfer

Sponsors

Vice Chancellor for Research , Tehran University of Medical Sceinces
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
16 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: couples undergoing ART with their own gametes; good and high responder women; women age less than 40, FSH level less than 10 mIU/ml on third day of mense, AMH more than 1.1 ng/ml; couples having at least one embryo available for transfer. Exclusion criteria: couples undergoing ART with donation gamate; azospermia; poor responder women: women age more than 40, FSH level more than 10 mIU/ml on third day of mense, AMH less than 1.1 ng/ml and less than 4 f0llicles in previous ART cycle.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: eight weeks after intervention. Method of measurement: vaginal sonography.

Secondary

MeasureTime frame
Implantation rate. Timepoint: Ten weeks after intervention. Method of measurement: vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeedeh Gharahjeh

Tehran University of Medical Sciences

s-gharahgeh@razi.tums.ac.ir Dr.gharahgeh_1388@yahoo.com+98 21 8490 2421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026