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Comparison of the efficacy of Sumatriptan, Pregabalin and Gabapentin on postoperative pain in rhinoplasty

Comparing the effect of single doses of preoperative use of Sumatriptan 100 milligram, Pregabalin 75 milligram and Gabapentin 300 milligram on postoperative pain in rhinoplasty

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20140503017537N7
Enrollment
90
Registered
2020-04-25
Start date
2020-03-09
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-operative pain after rhinoplasty. Acute pain, not elsewhere classified

Interventions

Intervention 1: Intervention group1: One hour before surgery, patients receive an oral capsule containing 100 mg Sumatriptan with 100 ml of drinking water. Intervention 2: Intervention group2: One hou

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult individuals volunteering for rhinoplasty with ASA I status.

Exclusion criteria

Exclusion criteria: Patients with a history of substance abuse, drug abuse or alcohol abuse Patients with kidney or liver failure Patients with diabetes or history of diabetes Patients who are allergic to any of the drugs used in this trial Patients who use antidiabetic medications, antidepressants, anticonvulsants or antihypertensive medications Patients who use painkillers daily or 24 hours before the surgery Patients who are unable to cooperate

Design outcomes

Primary

MeasureTime frame
Severity of postoperative pain. Timepoint: At 2,4,6,12,24 hours after the end of operation. Method of measurement: Using the Visual Analogue Scale(VAS).

Secondary

MeasureTime frame
Nausea and Vomiting. Timepoint: Within 24 hours after surgery. Method of measurement: Yes/No.;Drowsiness. Timepoint: Within 24 hours after surgery. Method of measurement: Yes/No.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Nazari

Kermanshah University of Medical Sciences

nazari.hamed67@yahoo.com+98 83 3729 6591

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026